Key result
Combined general and regional anesthesia for carotid endarterectomy is linked to improved hemodynamics and outcomes.
Why the study?
Peri-operative management of patients undergoing carotid endarterectomy is challenging due to major co-morbidities and high incidence of peri-operative stroke and myocardial infarction, with both general and regional anesthesia having pros and cons.
Does a combination of general and regional anesthesia improve hemodynamics and outcomes in patients undergoing carotid endarterectomy?
Case Report
Does a combination of general and regional anesthesia improve hemodynamics and outcomes in patients undergoing carotid endarterectomy?
A combination of general and regional anesthesia using ropivacaine and dexmedetomidine may offer improved hemodynamic stability and outcomes during carotid endarterectomy.
Hypothesis-generating for combined anesthesia in carotid endarterectomy; prospective trials needed before clinical adoption.
Carotid endarterectomy (CEA), a preventable surgery, reduces the future risks of cerebrovascular stroWke in patients with marked carotid stenosis. Peri-operative management of such patients is challenging due to associated major co-morbidities and high incidence of peri-operative stroke and myocardial infarction. Both general anesthesia (GA) and local regional anesthesia (LRA) can be used with their pros and cons. Most developing countries as well as some developed countries usually perform CEA under GA because of technical easiness. LRA usually comprises superficial, intermediate, deep cervical plexus block or a combination of these techniques. Deep block, particularly, is technically difficult and more complicated, whereas intermediate plexus block is technically easy and equally effective. We did CEA under a combination of GA and LRA using ropivacaine 0.375% with 1 mcg/kg dexmedetomidine (DEX) infiltration. In LRA, we gave combined superficial and intermediate cervical plexus block with infiltration at the incision site and along the lower border of mandible. We observed better hemodynamics in intraoperative as well as postoperative periods and an improved postoperative outcome of the patient. So, we concluded that combination of GA and LRA is a good anesthetic technique for CEA. Larger randomized prospective trials are needed to support our conclusion.
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Samanta et al. (2014) conducted a case report in Carotid stenosis. Combination of general anesthesia and local regional anesthesia was evaluated on Hemodynamics and postoperative outcome. A combination of general and local regional anesthesia using ropivacaine and dexmedetomidine for carotid endarterectomy resulted in better hemodynamics and improved postoperative outcomes.
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