Key result
A healthy diet lowers CVD incidence by reducing low-grade inflammation and microparticle shedding.
Why the study?
Identifying novel risk factors for cardiovascular disease and understanding how diet impacts atherothrombosis are important for developing preventive measures.
Does a healthy diet reduce the incidence of cardiovascular disease and progression of atherothrombosis?
Does a healthy diet reduce the incidence of cardiovascular disease and progression of atherothrombosis?
This review highlights the mechanisms by which a healthy diet reduces atherothrombosis and cardiovascular disease risk, including effects on microparticle shedding.
Supports dietary guidelines for CVD prevention; leaves open causal effects on microparticles pending RCTs.
Cardiovascular disease is the main cause of death worldwide, and is principally caused by atherosclerosis, with subsequent thrombus formation, eventually provoking an acute myocardial infarction or a stroke. The formation and progression of the atherosclerotic plaques responds to multiple factors including certain diets. Intensive research has elucidated the role of diet in cardiovascular disease and has led to public health policies focusing on educating the population on the role of nutrition in cardiovascular health. Compelling evidence shows that a healthy diet, rich in fruit and vegetables with moderate consumption of fish and a low consumption of animal by-products and processed foods, decreases low-grade inflammation and oxidation, leukocyte activation, platelet aggregation and microparticle shedding. Thus, following such a diet decreases the incidence of cardiovascular disease, lowers mortality and delays the progression of atherothrombosis. Identifying novel risk factors for cardiovascular disease and understanding how food impacts on the disease helps in the development of novel preventive measures.
No takes yet. Share an insight, caveat, or question.
Lina Badimón (2017) conducted a review in Cardiovascular disease and atherothrombosis. Healthy diet was evaluated. A healthy diet rich in fruits, vegetables, and moderate fish decreases low-grade inflammation, microparticle shedding, and the incidence of cardiovascular disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: