Key result
Pulmonary tumor microembolism syndrome occurs without prior malignancy or identifiable primary tumor at autopsy.
Why the study?
Pulmonary tumor microembolism is typically recognized in patients with known malignancy, but its occurrence without prior cancer history and undetectable primary tumor is unusual.
Case Report (n=1)
Clinicians should be aware that pulmonary tumor microembolism can affect patients without a known history of malignancy.
Pulmonary tumor microembolism warrants consideration without known malignancy; this Level 5 case leaves open its incidence and diagnostic approach.
Pulmonary tumor microembolism is usually recognized as a slowly progressive syndrome of dyspnea and pulmonary hypertension in a patient with an established diagnosis of malignant disease. We have reported an extremely unusual case in which the pulmonary tumor microembolism syndrome occurred in a patient without prior history of malignancy. Further, no primary tumor could be found on postmortem examination. Clinicians should be aware that this potentially treatable entity may affect a wider spectrum of patients than has been previously recognized.
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Margolis et al. (1985) conducted a case report in Pulmonary tumor microembolism (n=1). Pulmonary tumor microembolism syndrome occurred in a patient without a prior history of malignancy, and no primary tumor was found on postmortem examination.
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