Butyrate-Rich Diets Improve Redox Status and Fibrin Lysis in Behçet’s Syndrome

Behçet’s syndrome (BS) is a rare neutrophilic vasculitis characterized by arterial and venous events, uniquely treated by immunosuppressants rather than anticoagulants. We demonstrated in BS an impaired fibrinogen structure and fibrin susceptibility to plasmin-induced lysis, mainly due to an enhanced neutrophils reactive oxygen species (ROS) production, supporting the notion that BS is a model of inflammation-induced thrombosis .