Key result
Diabetes accelerates CVD via autonomic neuropathy, inflammation, and oxidative stress, requiring comprehensive risk management.
Why the study?
Diabetes mellitus is a major and independent risk factor for cardiovascular disease with complex pathophysiology and unmet needs for adequate cardiovascular protection despite hyperglycemia control.
Population
Close to 100 million patients worldwide with diabetes mellitus
Design
Review article
Authors
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Supports multifactorial risk control in diabetes; leaves open dominant mechanisms to prioritize targeted therapies.
Diabetes mellitus is an independent risk factor for cardiovascular disease, requiring a multifaceted approach and aggressive control of risk factors beyond just hyperglycemia.
Kolakalapudi et al. (2015) conducted a review in Diabetes Mellitus and Cardiovascular Disease. Diabetes mellitus accelerates cardiovascular disease through mechanisms including autonomic neuropathy, inflammation, and oxidative stress, requiring comprehensive management of all cardiovascular risk factors.
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