M. Guichard, B. Lachet, E. P. Malaise, Measurement of RBE, OER, and Recovery of Potentially Lethal Damage of a 645 MeV Helium Ion Beam Using EMT6 Cells, Radiation Research, Vol. 71, No. 2 (Aug., 1977), pp. 413-429
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Guichard et al. (1977) studied this question.