Key result
Higher BMI predicts ~37% lower all-cause mortality in idiopathic pulmonary arterial hypertension.
Why the study?
The association between obesity (indicated by BMI) and all-cause mortality in patients with idiopathic pulmonary arterial hypertension had not been clearly established.
Does higher BMI predict lower all-cause mortality in adult patients with idiopathic pulmonary arterial hypertension?
Cohort (n=78)
No
Does higher BMI predict lower all-cause mortality in adult patients with idiopathic pulmonary arterial hypertension?
Odds Ratio: 0.632 (95% CI 0.478–0.837)
p-value: p=0.001
Higher BMI is associated with improved survival in patients with idiopathic pulmonary arterial hypertension, demonstrating an obesity paradox in this population.
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Şentürk et al. (2020) conducted a cohort in idiopathic pulmonary arterial hypertension (n=78). Body-mass index (BMI) was evaluated on all-cause mortality (OR 0.632, 95% CI 0.478-0.837, p=0.001). Higher body-mass index was an independent predictor of lower all-cause mortality in patients with idiopathic pulmonary arterial hypertension (OR 0.632; 95% CI 0.478-0.837; p=0.001).
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