What question did this study set out to answer?

To evaluate the efficacy and feasibility of a 12-week moderate-intensity aerobic exercise regimen on body composition and metabolic parameters in overweight and obese individuals with gout.

September 5, 2022TrialsOpen Access

The effects of aerobic exercise on body composition in overweight and obese patients with gout: a randomized, open-labeled, controlled trial

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Authors

EJErtao Jia HZHaiqiong Zhu HGHongling Geng

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Overview

Randomized trial reports a protocol targeting body fat reduction in overweight and obese gout patients, suggesting structured aerobic exercise guidelines for clinical disease management.

Key Points

To evaluate the efficacy and feasibility of a 12-week moderate-intensity aerobic exercise regimen on body composition and metabolic parameters in overweight and obese individuals with gout.
Open-labeled randomized controlled trial (N=60; aged 18–55 years) allocating participants 1:1 to a moderate-intensity aerobic exercise group (MIAEG, n=30) or a non-exercising control group (CG, n=30; ChiCTR2200062153).
MIAEG participants engage in aerobic exercise targeting 60% heart rate reserve for 30–40 minutes per session, 3 days weekly across a 12-week intervention period, while controls maintain baseline habits.
Primary endpoint assesses the number of patients achieving body fat reduction at 12 weeks; secondary measures include changes in BMI, waist-to-hip ratio, serum uric acid, lipids, and insulin resistance compared via ANOVA.
Trial design and protocol paper; quantitative primary endpoint event rates, relative effect sizes, and p-values are pending trial completion.
The intervention protocol aims to determine whether individualized aerobic training systematically reduces total body fat compared to unaltered lifestyle controls.
Secondary analyses will quantify the magnitude and direction of exercise-induced changes on serum uric acid, lipid profiles, renal function, and hepatic steatosis.

Cite This Study

Jia et al. (2022) studied this question.

synapsesocial.com/papers/6aaa3012df35e3fdba844c89 https://doi.org/10.1186/s13063-022-06695-x

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September 5, 2022TrialsOpen Access

The effects of aerobic exercise on body composition in overweight and obese patients with gout: a randomized, open-labeled, controlled trial

View Full Paper

Ask AI

Bookmark

Authors

EJErtao Jia HZHaiqiong Zhu HGHongling Geng

Discussion

Member takes

Overview

Randomized trial reports a protocol targeting body fat reduction in overweight and obese gout patients, suggesting structured aerobic exercise guidelines for clinical disease management.

Key Points

To evaluate the efficacy and feasibility of a 12-week moderate-intensity aerobic exercise regimen on body composition and metabolic parameters in overweight and obese individuals with gout.
Open-labeled randomized controlled trial (N=60; aged 18–55 years) allocating participants 1:1 to a moderate-intensity aerobic exercise group (MIAEG, n=30) or a non-exercising control group (CG, n=30; ChiCTR2200062153).
MIAEG participants engage in aerobic exercise targeting 60% heart rate reserve for 30–40 minutes per session, 3 days weekly across a 12-week intervention period, while controls maintain baseline habits.
Primary endpoint assesses the number of patients achieving body fat reduction at 12 weeks; secondary measures include changes in BMI, waist-to-hip ratio, serum uric acid, lipids, and insulin resistance compared via ANOVA.
Trial design and protocol paper; quantitative primary endpoint event rates, relative effect sizes, and p-values are pending trial completion.
The intervention protocol aims to determine whether individualized aerobic training systematically reduces total body fat compared to unaltered lifestyle controls.
Secondary analyses will quantify the magnitude and direction of exercise-induced changes on serum uric acid, lipid profiles, renal function, and hepatic steatosis.

Cite This Study

Jia et al. (2022) studied this question.

synapsesocial.com/papers/6aaa3012df35e3fdba844c89 https://doi.org/10.1186/s13063-022-06695-x

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