Key result
Coronary intimal thickening affects up to ~70% of young Japanese and Chinese individuals.
Why the study?
Atherosclerosis requires a long time before clinical manifestation, necessitating comparative geographic pathology studies in youth to elucidate pathogenesis.
Observational
Comparative geographic pathology studies are needed to elucidate the pathogenesis of atherosclerosis in youth, requiring standardized methodology.
Although atherosclerosis is a typical adult disease in many countries, a long time period is required before its clinical manifestation can be observed. To elucidate pathogenesis, comparative studies on the geographic pathology of atherosclerosis in youth in Japan, China, and the United States have been carried out. First of all, our methodology should be discussed, especially with respect to extracellular or intracellular lipid and raised or non-raised lesions. Further study in this field will be of great importance.
No takes yet. Share an insight, caveat, or question.
Komatsu et al. (1991) conducted an observational in Atherosclerosis. Geographic and lifestyle factors was evaluated on Appearance rate of diffuse intimal thickening (DIT) and eccentric intimal thickening (EIT).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: