SARS-CoV-2 Seroprevalence among Healthcare, First Response, and Public Safety Personnel, Detroit Metropolitan Area, Michigan, USA, May–June 2020

H ealthcare, first response (e.g., firefighters, para- medics, emergency medical technicians), and public safety (e.g., law enforcement officers) personnel have served on the front lines of the coronavirus disease (COVID-19) pandemic response in several ca-pacities.Many of these occupations require intensive interaction with persons with suspected or confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.Both reverse transcription PCR (RT-PCR) testing for SARS-CoV-2 and assessing COVID-19 symptoms could be used to determine infection status, but not all infected persons develop symptoms or are tested within the necessary time window.Measuring antibodies to SARS-CoV-2 is necessary to inform our understanding of viral transmission dynamics in high-risk situations (1).The Centers for Disease Control and Prevention (CDC) collaborated with the Michigan Department of Health and Human Services (MDHHS) Region 2 South and North Healthcare Coalitions to invite personnel working onsite in hospital, first response, and public safety settings to be tested for SARS-CoV-2 antibodies and to complete a web-based survey about workplace, occupation, use of personal protective equipment (PPE), and selected exposures.The primary study objective was to estimate the prevalence of SARS-CoV-2 antibodies among this population.A second objective was to describe associations between seroprevalence and participant and workplace characteristics. MethodsThe MDHHS Region 2 South Healthcare Coalition area is the most populous region in Michigan and comprises Monroe, Washtenaw, and Wayne (including the city of Detroit) Counties.MDDHS Region 2 North Healthcare Coalition includes Macomb, Oakland, and St. Clair Counties.The Healthcare Coalitions coordinated with 27 hospitals and 7 MDHHS Medical Control Authorities (MCAs), which supervise and SARS-CoV-2 Seroprevalence among Healthcare, First Response, and Public Safety Personnel, Detroit Metropolitan Area, Michigan,