Key result
Rare hypoplastic coronary artery disease causes anterior MI in a 20-year-old man.
Why the study?
Hypoplastic coronary artery disease is a rare condition that may lead to myocardial infarction and sudden death, requiring awareness in young patients with MI.
Case Report (n=1)
Hypoplastic coronary artery disease is a rare condition that should be considered in the differential diagnosis for children and young adults presenting with myocardial infarction or sudden cardiac death.
May warrant consideration of hypoplastic coronary artery disease in young MI patients; leaves open questions on prevalence and management.
Hypoplastic coronary artery disease (HCAD) is a rare condition that may lead to myocardial infarction (MI) and sudden death. We discovered HCAD in a young man who developed chest pain after heavy drinking and who was found to have suffered an MI. His ECG showed ST-segment elevation with Q waves in the anterior leads, and echocardiography revealed apical dyskinesia with moderate left ventricular (LV) dysfunction. Coronary angiography showed hypoplasia of the left anterior descending (LAD) artery. (99m)Tc-tetrofosmin-gated myocardial perfusion scintigraphy showed a large, fixed perfusion defect in the anteroseptal and apical segments. Sixty-four-slice cardiac CT and cardiac MR imaging demonstrated thinning of the apical wall with calcification and delayed enhancement, supporting the diagnosis of long-standing MI. The patient was discharged symptom-free on medication for ischemic heart failure two weeks after admission. Although HCAD is very uncommon, it should be considered in children and young adults who suffer MI or sudden cardiac death.
No takes yet. Share an insight, caveat, or question.
Sim et al. (2009) conducted a case report in Myocardial Infarction and Hypoplastic Coronary Artery Disease (n=1). Hypoplastic coronary artery disease was evaluated on Myocardial infarction. Hypoplastic coronary artery disease, a rare congenital anomaly, was identified as the cause of an anterior myocardial infarction in a 20-year-old man.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: