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October 12, 2007Archives of Disease in Childhood

Should Gonadotropin Releasing Hormone Analogue Be Administered to Prevent Premature Ovarian Failure in Young Women With Systemic Lupus Erythematosus on Cyclophosphamide Therapy?

Rajiv Sinha Janis M. Dionne

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Abstract

1) Young women suffering from SLE treated with CYC have a high risk of ovarian failure. [Grade C] 2) GnRH is a promising option for ovarian preservation in SLE but should currently be regarded as an experimental therapy.

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Sinha et al. (2007) studied this question.

synapsesocial.com/papers/6aaa3a956a46b5e7d4a88113 https://doi.org/10.1136/adc.2007.131334

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