Key result
Each unit increase in residual CatLet score is linked to ~4% higher MACE risk post-PCI.
Why the study?
The utility of the residual CatLet score and its derived indexes for predicting outcomes in patients with chronic coronary syndrome after PCI was not well established.
Do the residual CatLet score (rCS) and Catlet revascularization index (CRI) predict long-term outcomes in patients with chronic coronary syndrome after PCI?
Cohort (n=262)
No
Do the residual CatLet score (rCS) and Catlet revascularization index (CRI) predict long-term outcomes in patients with chronic coronary syndrome after PCI?
Hazard Ratio: 1.04 (95% CI 1.02–1.05)
p-value: p=<0.001
The residual CatLet score (rCS) is a superior predictor of long-term MACEs compared to the Catlet revascularization index (CRI) in patients with chronic coronary syndrome undergoing PCI.
Residual CatLet score may refine post-PCI risk stratification in chronic coronary syndrome; hypothesis-generating and requires prospective validation before adoption.
Background Coronary Artery Tree description and Lesion EvaluaTion (CatLet) angiographic scoring (CS) system, reflecting coronary artery variability, is a newly developed scoring tool for assessing the degree of coronary artery stenosis. And the residual CatLet score (rCS) has reflected the burden of residual lesions. This study was conducted to explore the utility of the rCS and its derived indexes-Catlet revascularization index (CRI) among patient with chronic coronary syndrome (CCS) after percutaneous coronary intervention (PCI). Methods A study cohort was established comprising patients who received PCI in the Second Affiliated Hospital of Wannan Medical College from May 2019 to July 2020. Patients were divided into tertiles according to the CRI and rCS values. The primary endpoint was major adverse cardiac events (MACEs), including myocardial infarction, cardiac death, heart failure and all-cause mortality, secondary outcome measures were recurrent angina. Results A total of 262 patients were enrolled in this analysis, with mean CRI and rCS scores of 58.08 ± 27.88 and 17.33 ± 15.81, respectively. Kaplan–Meier analysis revealed that higher levels of residual coronary lesions, as measured by rCS and its derivatives, correlated with a higher incidence of adverse cardiovascular events. Multivariable Cox regression analysis demonstrated that CRI [hazard ratio (HR): 0.98; 95% confidence interval (CI): 0.98–0.99; p < 0.001] and rCS (HR: 1.04; 95% CI: 1.02–1.05; p < 0.001) were significant independent predictors of MACEs during long-term follow-up; CRI (HR 0.98, 95% CI 0.98–0.99; p < 0.001) and rCS (HR 1.05, 95% CI 1.03–1.07; p < 0.001) emerged as significant predictors for the risk of recurrent angina. rCS demonstrated superior discriminative ability for MACEs compared to CRI at 6.2 years, with area under the curve values of 0.73 and 0.67, respectively ( p < 0.001). Conclusion This real-world analysis of CCS patients undergoing PCI demonstrated that the rCatlet score offered superior predictive performance for long-term MACEs compared to the CRI.
No takes yet. Share an insight, caveat, or question.
Wang et al. (2026) conducted a cohort in Chronic coronary syndrome (n=262). Residual CatLet score (rCS) vs. Lower residual CatLet score was evaluated on Major adverse cardiac events (MACEs) (HR 1.04, 95% CI 1.02-1.05, p=<0.001). Each one-unit increase in the residual CatLet score was independently associated with a higher risk of major adverse cardiac events (HR 1.04) in patients with chronic coronary syndrome after PCI.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: