Key result
Gastric bypass linked to ~9-fold higher odds of successful weight loss versus gastric band.
Why the study?
Gastric bypass and gastric band are the most common obesity surgeries in the US, but few reports have compared their weight loss outcomes and variability.
Does gastric bypass improve excess weight loss compared to gastric band in severely obese adults?
Population
1,733 severely obese adults aged 18-65 years meeting NIH criteria for obesity surgery
Comparison
Gastric bypass vs gastric band
Design
Cohort study with patient/surgeon procedure selection
Follow-up
2 years
Authors
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May favor gastric bypass for weight-loss targets in observational data; leaves open need for randomized confirmation before practice change.
Cohort (n=1,518)
Does gastric bypass improve excess weight loss compared to gastric band in severely obese adults?
Odds Ratio: 9.1
p-value: p=<0.0001
Gastric bypass produces more rapid, greater, and more consistent excess weight loss over a 2-year period compared to gastric band in severely obese adults.
Puzziferri et al. (2008) conducted a cohort in Severe obesity (n=1,518). Gastric bypass vs. Gastric band was evaluated on Successful weight loss (≥40% excess weight loss) (OR 9.1, p=<0.0001). Gastric bypass was associated with a greater likelihood of achieving ≥40% excess weight loss at 24 months compared with gastric band (OR 9.1; P<0.0001).