Key result
Major elective cancer surgery is linked to improved 6-month quality of life in older adults.
Why the study?
Accurate quality of life data and functional results after cancer surgery are lacking for older patients.
Does major elective cancer surgery affect quality of life in older adults?
Population
942 older adults (≥70 years) undergoing major elective cancer surgery across 26 centers
Comparison
QoL before vs after major elective cancer surgery
Design
International multicenter prospective cohort study
Follow-up
180 days
Authors
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Supports potential QoL benefit at 6 months; hypothesis-generating and should not change practice without RCTs.
Cohort (n=942)
Yes
Does major elective cancer surgery affect quality of life in older adults?
Absolute Event Rate: 0.82% vs 0.79%
p-value: p=< .001
Older adults' preoperative quality of life is preserved at 3 months and improves at 6 months after major cancer surgery.
Montroni et al. (2022) conducted a cohort in Cancer (n=942). Major elective cancer surgery vs. Preoperative baseline was evaluated on Mean EQ-5D-3L quality of life index (p=< .001). Major elective cancer surgery in older adults was associated with an improved mean EQ-5D-3L quality of life index at 6 months compared to preoperative baseline (0.82 vs 0.79; P < .001).
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