Case report reveals a rare non-HPV squamous cell papilloma of the bladder mimicking malignancy in an older male, highlighting the need for surveillance due to recurrence risk.
Squamous cell lesions of the urinary bladder are generally rare. Herein we describe a case of 74-year-old male patient with a benign squamous cell papilloma. Histologically, the tumor presented extensive keratinization at its surface and showed no nuclear atypia or stromal invasion. The tumor cells were negative for HPV DNA. These lesions are extremely rare, and even though they are considered benign and non-HPV related, they should be followed, since recurrence has been reported.
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Miliaras et al. (2013) studied this question.
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