Key result
Nonconventional MRI better tracks serial changes in newly forming multiple sclerosis lesions than conventional imaging.
Why the study?
Conventional MRI techniques are sensitive in detecting MS lesions but correlate weakly with clinical manifestations and irreversible disability, necessitating better imaging methods.
Do nonconventional MRI techniques provide a better approximation of the pathological substrate of MS plaques compared to conventional MRI?
Population
Patients with multiple sclerosis
Comparison
Nonconventional MRI techniques vs conventional MRI techniques
Design
Review
Authors
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May support nonconventional MRI in MS research; does not yet justify replacing conventional sequences in practice.
Do nonconventional MRI techniques provide a better approximation of the pathological substrate of MS plaques compared to conventional MRI?
Nonconventional MRI techniques offer improved assessment of the pathological substrate and serial changes in MS lesions compared to conventional MRI.
Rovira et al. (2013) conducted a review in Multiple sclerosis. Nonconventional MRI techniques vs. Conventional MRI techniques was evaluated. Nonconventional MRI techniques, such as magnetization transfer and diffusion-weighted imaging, better assess serial changes in newly forming lesions in multiple sclerosis than conventional MRI.