Key result
Prenatal diagnosis of d-TGA was associated with lower mean direct hospitalization costs compared to postnatal diagnosis ($88,305 vs $108,014), although not statistically significant (P=.31).
Why the study?
The impact of prenatal diagnosis of complete transposition of the great arteries on total hospital costs was not well described.
Does prenatal diagnosis reduce total hospital costs in infants with complete transposition of the great arteries compared to postnatal diagnosis?
Cohort (n=33)
No
Does prenatal diagnosis reduce total hospital costs in infants with complete transposition of the great arteries compared to postnatal diagnosis?
Absolute Event Rate: 88305% vs 108014%
p-value: p=.31
Prenatal diagnosis of d-TGA may be associated with lower total hospital costs compared to postnatal diagnosis, though the difference was not statistically significant in this small cohort.
OBJECTIVE: Prenatal diagnosis of congenital heart disease (CHD) is associated with improved clinical outcomes, yet its impact on the cost of hospitalization is not well described. We hypothesized that prenatal diagnosis of complete transposition of the great arteries (d-TGA) results in lower total hospital costs compared with postnatal diagnosis. METHODS: Retrospective analysis of infants with d-TGA repaired at our center from July 2006 to 2014. Total charges from initial hospitalization until discharge were converted to costs using the cost-to-charge ratio and then converted into 2016 dollars using the consumer price index. A direct cost comparison from the hospital perspective was performed between groups. A secondary analysis included the cost of prenatal diagnosis. RESULTS: Thirty-three infants with d-TGA were identified; 8 with and 25 without prenatal diagnosis. There was no difference in baseline characteristics. Mean direct cost of hospitalization was higher in infants without prenatal diagnosis ($108 014 ± $51 305 vs $88 305 ± $22 896, P = .31). On secondary analysis, the cost of prenatal diagnosis was negligible compared with total hospital cost. CONCLUSIONS: Total cost of initial hospitalization was higher for infants without prenatal diagnosis of d-TGA. Prenatal diagnosis not only improves clinical outcomes but may also be cost saving in the current era of increasing health care costs.
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Gupta et al. (2018) conducted a cohort in Complete transposition of the great arteries (d-TGA) (n=33). Prenatal diagnosis vs. Postnatal diagnosis (without prenatal diagnosis) was evaluated on Mean direct cost of hospitalization (p=.31). Prenatal diagnosis of d-TGA was associated with lower mean direct hospitalization costs compared to postnatal diagnosis ($88,305 vs $108,014), although not statistically significant (P=.31).
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