Key result
Prospective ECG-triggered CCTA achieves ~97% assessable coronary segments with low radiation exposure.
Why the study?
A systematic review was needed to evaluate the diagnostic accuracy, image quality, and radiation dose of prospective ECG-triggered coronary computed tomography angiography.
Does prospective ECG-triggered CCTA provide high diagnostic accuracy and image quality with low radiation dose?
Systematic Review (n=2,080)
Does prospective ECG-triggered CCTA provide high diagnostic accuracy and image quality with low radiation dose?
Prospective ECG-triggered CCTA provides high diagnostic accuracy and image quality while maintaining a low radiation dose.
Supports prospective ECG-triggered CCTA for CAD assessment with minimized radiation; confirms high segment assessability across aggregated studies.
The purpose of this study was to perform a systematic review of the diagnostic accuracy, image quality and radiation dose of prospective electrocardiography (ECG)-triggered coronary computed tomography angiography (CCTA). We searched databases containing studies of CCTA that used prospective ECG-triggering between 2008 and 2011. The effective dose and image quality reported in each study were analysed and compared between the types of multislice CT scanners. We identified 23 studies through this search, with mean assessable coronary segments and effective dose at 96.8% (95% confidence level [CI] 83%, 100%) and 3.6 mSv (95% CI 2.9, 4.3 mSv), respectively. Both quantitative and qualitative assessments of image quality indicated that image quality was achieved in studies using prospective ECG-triggered CCTA, regardless of the type of CT scanners. The pooled estimates of diagnostic values were more than 90% for patient-, vessel- and segment-based assessments. Prospective ECG-triggered CCTA results in high diagnostic accuracy and image quality, with a significantly low radiation dose.
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Sabarudin et al. (2013) conducted a systematic review in Suspected or confirmed coronary artery disease (n=2,080). Prospective ECG-triggered coronary computed tomography angiography (CCTA) was evaluated on Mean assessable coronary segments (95% CI 83.0-100.0). Prospective ECG-triggered CCTA achieved a high mean percentage of assessable coronary segments (96.8%) and a low mean effective radiation dose (3.6 mSv) for the assessment of coronary artery disease.
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