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January 1, 2015Clinical Pharmacology & BiopharmaceuticsOpen Access

The Synergistic Effects of Pioglitazone on the Glucose-Lowering Action of Metformin in Relation to OCT1 and Gluts m-RNA Expression in Healthy Volunteer

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A 2015 study studied this question.

synapsesocial.com/papers/6aaa539a3266ecd0486cb863 https://doi.org/10.4172/2167-065x.1000129

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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1Insulin Resistance versus Insulin Deficiency in Non-Insulin-Dependent Diabetes Mellitus: Problems and Prospects1998 · 436 citations
2Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action2007 · 971 citations
3Mechanism by which metformin reduces glucose production in type 2 diabetes.2000 · 1,059 citations
4Cloning and Characterization of Two Human Polyspecific Organic Cation Transporters1997 · 639 citations