Key result
APACHE II scores ≥20 linked to increased postoperative mortality in colonic perforation.
Why the study?
The significance of scoring systems assessing severity and prognostic factors in patients with colonic perforation was unclear.
Do scoring systems (APACHE II, MPI, PIA II) and clinical factors predict mortality in patients undergoing emergency operation for colorectal perforation?
Population
26 patients undergoing emergency operation for colorectal perforation
Comparison
APACHE II, Mannheim peritonitis index, and peritonitis index of Altona scores and clinical factors
Design
Observational study
Authors
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APACHE II ≥20 was associated with higher mortality in colonic perforation; leaves open its added value for risk stratification in prospective cohorts.
Observational (n=26)
No
Do scoring systems (APACHE II, MPI, PIA II) and clinical factors predict mortality in patients undergoing emergency operation for colorectal perforation?
p-value: p=0.00003
Pre- and postoperative blood pressure, serum creatinine, and APACHE II score (especially >=20) are strong prognostic factors for mortality in patients with colonic perforation.
Atsushi Horiuchi (2007) conducted an observational in colonic perforation (n=26). APACHE II score was evaluated on postoperative mortality (p=0.00003). APACHE II scores were significantly higher in non-survivors than survivors of colonic perforation (19.3 vs 10.4, P=0.00003), with scores ≥20 associated with increased mortality.
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