Key result
MDCT reveals at least two typical radiological findings in ~92% of patients with PVOD.
Why the study?
Definitive diagnosis of PVOD is complex without histological or genetic confirmation, making MDCT an essential non-invasive diagnostic tool to guide treatment and assess lung transplantation.
Population
25 patients diagnosed with PVOD (9 sporadic and 16 hereditary)
Comparison
Sporadic form vs hereditary form of PVOD
Design
Retrospective review of a consecutive series
Authors
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MDCT aids PVOD suspicion in most cases but a subtle scan does not exclude it; leaves open prospective validation of diagnostic thresholds.
Observational (n=25)
Typical MDCT findings are highly prevalent in PVOD but do not correlate with hemodynamic severity, indicating that a poorly expressive scan does not rule out the disease.
Núñez et al. (2021) conducted an observational in Pulmonary veno-occlusive disease (PVOD) (n=25). Multidetector computed tomography (MDCT) was evaluated on Presence of at least two typical radiological findings (ground glass parenchymal involvement, septal lines, and lymphadenopathy). MDCT revealed at least two typical radiological findings in 92% of patients with pulmonary veno-occlusive disease, with no significant differences between hereditary and sporadic forms.
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