Progression of Pancreatic Morphologic Changes and Endocrine Dysfunction After Acute Pancreatitis: Preliminary Results of the Longitudinal Goulash-Plus Cohort Study

Approximately 96% to 98% of patients survive acute pancreatitis (AP),1 yet many are exposed to significant long-term risks that are often overlooked. AP may be followed by recurrent acute pancreatitis (RAP) episodes and early chronic pancreatitis (ECP), which can eventually progress to chronic pancreatitis (CP).2,3 Progression of endocrine dysfunction, defined as the combined proportion of newly diagnosed prediabetes and diabetes mellitus (DM), may also reach 35% in the first year after the first AP episode and 59% in the fifth year.