Key result
Sucralfate reduces median postoperative throat pain scores by ~25% versus placebo.
Why the study?
Does sucralfate reduce pain and morbidity in post-tonsillectomy patients?
RCT (n=56)
Computer-generated random numbers
No
Does sucralfate reduce pain and morbidity in post-tonsillectomy patients?
Absolute Event Rate: 6% vs 8%
p-value: p=0.001
Sucralfate may reduce post-tonsillectomy pain and speed oral intake; confirms benefit in this RCT.
Tonsillectomy is one of the commonest surgical procedures done in otolaryngology. Nonetheless, pain remains an important post-operative morbidity regarding patient well being as it may lead to secondary infection, bleeding and dehydration. Pain affects the oral intake of the child and thereby nourishment; leading to delayed wound healing, lack of wellbeing, prolonged hospital stay and financial burden both to the child and its parents.
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Arun Alexander (2018) conducted an RCT in Post-tonsillectomy pain and morbidity (n=56). Sucralfate vs. Placebo (Glucose 1g in 50ml distilled water) was evaluated on Median throat pain score on postoperative day 2 (p=0.001).
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