Key result
Acute infectious mononucleosis increases spleen length by ~34% from baseline in collegiate athletes.
Why the study?
The degree, timing, and resolution of splenic enlargement in collegiate athletes with acute infectious mononucleosis were not quantitatively characterized.
What is the degree, rate, and resolution time of splenic enlargement in athletes with acute infectious mononucleosis?
Cohort (n=20)
Yes
What is the degree, rate, and resolution time of splenic enlargement in athletes with acute infectious mononucleosis?
In athletes with infectious mononucleosis, peak splenic enlargement occurs within 2 weeks of symptom onset and resolves within 4-6 weeks, providing a predictable timeline for return-to-play decisions.
No takes yet. Share an insight, caveat, or question.
May inform extended splenic monitoring in athletes with mononucleosis; leaves open prospective validation for return-to-play protocols.
Hosey et al. (2008) conducted a cohort in Acute infectious mononucleosis (n=20). Acute infectious mononucleosis vs. Baseline was evaluated on Per cent enlargement of spleen size (length) from baseline, time to maximum splenic length, and time to resolution.. In collegiate athletes with acute infectious mononucleosis, maximum splenic length increased by a mean of 33.6% from baseline, peaking at a mean of 12.3 days from symptom onset.
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