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March 2, 2021Kardiologia PolskaOpen Access

Smoking cessation in patients with established coronary artery disease: data from the POLASPIRE survey

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Key result

Secondhand smoke exposure linked to ~127% greater risk of persistent smoking after CAD hospitalization.

  • OR 2.27
  • 95% CI 1.35-3.84
  • P=0.002
  • n=1,034

Why the study?

Smoking cessation in patients with CAD reduces cardiovascular events, but factors related to persistent smoking needed evaluation.

What factors are associated with persistent smoking in patients with established coronary artery disease?

Population

1034 patients aged 80 years or younger hospitalized for ACS or myocardial revascularization

Comparison

Persistent smokers vs patients who quit smoking

Design

Survey

Follow-up

6 to 18 months

Authors

PKPaweł KoziełPostgraduate School of Molecular MedicinePJPiotr JankowskiPreventive CardiologyDKDariusz A. KosiorMinistry of Internal Affairs of the Republic of Tajikistan

Discussion

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Implication

Persistent smoking after CAD hospitalization supports enhanced cessation efforts; hypothesis-generating for secondhand smoke exposure as a modifiable factor.

Study Design

Type

Cross-Sectional (n=1,034)

Multicenter

Yes

Structured PICO

What factors are associated with persistent smoking in patients with established coronary artery disease?

P
Population
1,034 patients aged 18 to 80 years with established coronary artery disease, hospitalized for acute coronary syndrome or revascularization 6 to 18 months prior.
O
Outcome
Persistent smoking (smoking at the time of interview among those who smoked during the month prior to the recruiting event)patient reported

Main Result

Odds Ratio: 2.27 (95% CI 1.35–3.84)

p-value: p=0.002

More than half of patients who smoke prior to hospitalization for CAD continue to smoke 6 to 18 months later, highlighting a need for targeted cessation strategies.

Limitations

  • Cross-sectional design does not allow addressing causality
  • Unable to assess the relation between smoking status and the risk of cardiovascular complications
  • Participants were limited to those who had experienced an acute CAD event or had undergone a revascularization procedure, so not representative of all CAD patients
  • Only included patients aged 80 years or younger

Cite This Study

Kozieł et al. (2021) conducted a cross-sectional in Coronary artery disease (n=1,034). Secondhand smoke exposure vs. No secondhand smoke exposure was evaluated on Persistent smoking at 6 to 18 months follow-up (OR 2.27, 95% CI 1.35-3.84, p=0.002). Over half (54.7%) of smokers hospitalized for coronary artery disease remained persistent smokers 6 to 18 months after discharge, with secondhand smoke exposure significantly increasing this risk (OR 2.27).

synapsesocial.com/papers/6aaa594d1bc0677246be05a7https://doi.org/10.33963/kp.15854

Topics

Coronary artery disease
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Also Consider

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  1. 1Practice setting and secondary prevention of coronary artery disease2017 · 41 citations
  2. 2Secondary prevention of coronary artery disease in Poland. Results from the POLASPIRE survey2020 · 41 citations
  3. 3Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry2019 · 974 citations
  4. 4Time Trends in Lifestyle, Risk Factor Control, and Use of Evidence-Based Medications in Patients With Coronary Heart Disease in Europe: Results From 3 EUROASPIRE Surveys, 1999–20132016 · 117 citations
  5. 52016 European Guidelines on cardiovascular disease prevention in clinical practice2016 · 1,358 citations