Key result
Serum cystatin C may offer greater GFR sensitivity than serum creatinine in elderly populations.
Why the study?
Early identification of nephropathy in elderly patients is crucial, but the usefulness of serum cystatin C as a marker of renal function has not been extensively examined in large elderly populations.
Population
Large elderly population
Comparison
Serum cystatin C vs serum creatinine and microalbuminuria
Authors
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Should not yet alter GFR estimation practice in elderly; leaves open cystatin C superiority without quantitative data.
Wasén et al. (2002) studied Kidney dysfunction. Serum Cystatin C vs. Serum creatinine was evaluated. Serum cystatin C is discussed as a potentially more sensitive indicator of glomerular filtration rate than serum creatinine in elderly populations, though no quantitative results are reported.
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