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September 1, 2016BMJ OpenOpen Access

Antipsychotic prescribing in care homes before and after launch of a national dementia strategy: an observational study in English institutions over a 4-year period

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Authors

ASAla SzczepuraUniversity of LondonDWDeidre WildCoventry UniversityAKAmir KhanInstitute of Business Administration Karachi

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Overview

Observational study reveals unchanged antipsychotic prescribing rates in dementia care home residents after strategy launch, highlighting persistent excessive treatment durations.

Key Points

  • To evaluate the association between the launch of the National Dementia Strategy and antipsychotic prescribing patterns in long-term residential care facilities across England.
  • Retrospective observational analysis of electronic medicines management data from 616 long-term care institutions comprising 31,619 residents over a 4-year period following strategy implementation.
  • Assessed antipsychotic point prevalence, dosage levels, treatment durations, and the proportion of second-generation versus first-generation agents across institutional characteristics and geographical regions.
  • Overall antipsychotic prescribing rates did not change significantly across the 4-year period (Kolmogorov-Smirnov test p=0.60), nor was there a significant transition toward second-generation agents (p=0.32).
  • Treatment duration exceeded recommended limits in 69.7% of cases, while dosage exceeded maximum indicated levels in only 1.3% of cases.
  • High-prescribing homes were significantly associated with location in deprived areas (RR=5.89, 95% CI 4.35 to 7.99, p<0.001) and registration for dementia care (RR=3.38, 95% CI 3.06 to 3.73, p<0.001), showing a sixfold regional variation.

Cite This Study

Szczepura et al. (2016) studied this question.

synapsesocial.com/papers/6aaa5d100d3342aa3754cc3bhttps://doi.org/10.1136/bmjopen-2015-009882
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