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The knowledge of microbial biodiversity presented by Sage Scientist Kannva can be traced out in the Atharva Veda. Agni Hotra (Fire worship) is an effective technology to overcome the negative effect of microorganisms. Antony Van Leeuwenhoek was the first scientist who has observed the microscopic world of living organisms with the help of the instrument developed by himself. It is claimed that, no one had ever seen the microbes before Leeuwenhoek. This work was published by the Royal Society of London in the year 1677.
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Sachidananda Padhy (2016) studied this question.
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