Key result
Stroke volume variation predicts fluid responsiveness moderately before AVR and well postoperatively, reaching AUC 0.90.
Why the study?
Prediction of fluid responsiveness using dynamic variables has not been sufficiently studied in patients undergoing aortic stenosis surgery.
Do dynamic variables predict fluid responsiveness in mechanically ventilated patients undergoing aortic valve replacement for aortic stenosis?
Population
31 analysed patients scheduled for aortic valve replacement due to aortic stenosis on mechanical ventilation
Comparison
Fluid responsiveness before vs after aortic valve replacement using dynamic variables
Design
Observational study
Follow-up
Perioperative (before and after valve replacement)
Authors
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SVV may guide postoperative fluid decisions in AVR but not preoperatively; leaves open prospective validation in aortic stenosis.
Observational (n=31)
Do dynamic variables predict fluid responsiveness in mechanically ventilated patients undergoing aortic valve replacement for aortic stenosis?
Effect estimate: AUC 0.77 (95% CI 0.58-0.90)
Arterial pressure-based dynamic variables have limited ability to predict fluid responsiveness before aortic valve replacement but perform well postoperatively.
Høiseth et al. (2014) conducted an observational in Aortic stenosis (n=31). Dynamic variables (stroke volume variation, pulse pressure variation, Pleth variability index) was evaluated on Fluid responsiveness (increase in stroke volume ≥ 15% to a fluid challenge) predicted by stroke volume variation before surgery (AUC 0.77, 95% CI 0.58-0.90). Stroke volume variation predicted fluid responsiveness moderately before aortic valve replacement (AUC 0.77; 95% CI 0.58-0.90) and well postoperatively (AUC 0.90; 95% CI 0.74-0.98).
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