Key result
Endometrial radiotherapy linked to fatal peritoneal angiosarcoma 17 years later in a rare case.
Why the study?
Peritoneal angiosarcoma is an extremely rare tumour with variable presentation, making diagnosis and management challenging.
Case Report (n=1)
Peritoneal angiosarcoma is a rare and aggressive tumor that can present with haemorrhagic ascites years after pelvic radiotherapy, posing significant diagnostic and therapeutic challenges.
Angiosarcomas account for only 1-2% of all soft tissue sarcomas, with the most common site of origin being in the head and neck region. Peritoneal angiosarcoma is an extremely rare tumour and few cases have been reported previously. Presentation of peritoneal angiosarcoma can be very variable, hence making diagnosis difficult. Herein, we review the current literature and describe a rare case of a patient who presented with haemorrhagic ascites, 17 years after radiotherapy for endometrial carcinoma and was subsequently diagnosed with peritoneal angiosarcoma. Due to extensive disease, surgery was not a viable option. She was started on palliative chemotherapy, but despite treatment, her condition deteriorated further and she eventually passed away. We highlight the diagnostic challenges and considerations in these patients as well as current treatment and management options available.
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Seo et al. (2017) conducted a case report in Peritoneal angiosarcoma (n=1). Radiotherapy was evaluated on Clinical course and survival. A patient developed fatal peritoneal angiosarcoma 17 years after receiving radiotherapy for endometrial carcinoma, highlighting the diagnostic challenges and poor prognosis of this rare tumor.
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