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At baseline, within-group comparisons in all groups found statistically significant differences (SSD; p < 0.001) only between the endmost RPs (‘A’ vs. ‘H’), for all CPs, LPs and BMD values in the absence of SSD in mJSW. During the observation, for all groups, SSDs (p < 0.05) were detected between all RPs (‘H’ vs. ‘I’ vs. ‘A’), for all assessed indicators, but at different time points according to applied treatment. Furthermore, between groups comparisons found SSD at М12 in JSN for both stages K/L-II (p = 0.004) /K/L-III (p = 0.003), in all RPs of MMW-HA vs. NS. These findings were accompanied by similar changes in mJSW (p < 0.001) found at M36 and in times to conversions to total hip replacement (tTHR) - MMW-HA vs. NS (p < 0.001).
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Sapundzhiev et al. (2022) studied this question.
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