Key result
Lower adiponectin plays a major role in obesity-related insulin resistance and atherosclerosis.
Why the study?
Adiponectin plays a major role in obesity-related insulin resistance and atherosclerosis, but its implications in the pathophysiology and treatment of insulin resistance and NAFLD require summarization.
Design
Review article
Authors
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Adiponectin may inform metabolic risk stratification in obesity; leaves open its diagnostic or therapeutic utility pending trials.
Adiponectin is a key adipocytokine whose decreased levels are implicated in obesity-related insulin resistance and non-alcoholic fatty liver disease.
Méndez‐Sánchez et al. (2006) conducted a review in Non-alcoholic fatty liver disease and insulin resistance. Adiponectin was evaluated. Adiponectin is an adipocyte-derived hormone whose concentrations are decreased in insulin-resistant subjects, playing a major role in obesity-related insulin resistance and atherosclerosis.
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