Key result
Unsupplemented nitrous oxide shows no major hemodynamic changes in cardiac patients beyond transient intubation spikes.
Why the study?
The haemodynamic effects of unsupplemented nitrous oxide in about 30% oxygen in cardiac patients were not well characterized.
Does unsupplemented nitrous oxide in 30% oxygen cause significant haemodynamic changes compared to air breathing in cardiac patients?
Population
Five cardiac patients
Comparison
Unsupplemented nitrous oxide in about 30% oxygen with and without IPPV vs air breathing at rest
Design
Observational study comparing haemodynamics during anaesthesia and control periods
Authors
Loading...
May support nitrous oxide stability in cardiac patients; leaves open confirmation in randomized trials.
Does unsupplemented nitrous oxide in 30% oxygen cause significant haemodynamic changes compared to air breathing in cardiac patients?
Unsupplemented nitrous oxide in 30% oxygen is haemodynamically stable in cardiac patients, supporting its safety and clinical use in this population.
Dottori et al. (1976) studied Cardiac patients (n=5). Unsupplemented nitrous oxide in about 30% oxygen, with and without IPPV vs. Control periods at rest with air breathing was evaluated on Systemic and pulmonary circulation (haemodynamic changes). Unsupplemented nitrous oxide in about 30% oxygen did not cause great haemodynamic changes in cardiac patients, though transient increases in blood pressures occurred during tracheal intubation.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: