Key result
Mitral valve repair improves clinical status and reduces cardiothoracic ratio in 4 adolescents with endomyocardial fibrosis.
Why the study?
Mitral valve repair as a treatment for severe mitral insufficiency in localized left ventricular endomyocardial fibrosis without papillary muscle endocardiectomy is not well established.
Does mitral valve repair improve clinical outcomes in adolescent patients with left ventricular endomyocardial fibrosis and severe mitral insufficiency?
Case Report (n=4)
Does mitral valve repair improve clinical outcomes in adolescent patients with left ventricular endomyocardial fibrosis and severe mitral insufficiency?
Mitral valve repair appears to be an effective and preferred treatment for severe mitral insufficiency in localized left ventricular endomyocardial fibrosis where endocardiectomy is not required.
May support mitral valve repair in select adolescent cases; hypothesis-generating and requires prospective validation.
Left ventricular endomyocardial fibrosis accompanied by severe mitral insufficiency occurring in 4 adolescent African patients is reported. Mitral valve repair was successfully performed in all 4 cases including annuloplasty in 3 and chordal shortening in one. Short-term follow-up of up to 10 months indicated substantial clinical improvement and decrease of the cardiothoracic ratio in all. It is emphasized that mitral valve repair appears to be the method of choice in treating mitral incompetence in the localized form of endomyocardial fibrosis, where endocardiectomy is not required in the area of the papillary muscles.
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Métras et al. (1983) conducted a case report in Left ventricular endomyocardial fibrosis with severe mitral insufficiency (n=4). Mitral valve repair was evaluated on Clinical improvement and decrease of cardiothoracic ratio. Mitral valve repair resulted in substantial clinical improvement and decreased cardiothoracic ratio in all 4 adolescent patients with left ventricular endomyocardial fibrosis and severe mitral insufficiency.
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