Key result
Diabetes lasting 5 to 10 years is linked to ~30% silent ischemia, driving subclinical cardiac dysfunction.
Why the study?
Diabetes mellitus is associated with cardiovascular disease and related complications, but the assessment of cardiac function and its relation to glycaemic control in diabetic patients requires further evaluation.
Cross-Sectional (n=30)
No
In patients with diabetes of 5-10 years duration, subclinical ischemic heart disease and diastolic dysfunction are common even in the absence of overt cardiac symptoms.
May support subclinical cardiac screening in asymptomatic mid-duration diabetes; hypothesis-generating for ischemia's role in dysfunction.
BACKGROUNDDiabetes mellitus is associated with long-term organ complications, microvascular and macrovascular.It is associated with cardiovascular disease, which is correlated to microalbuminuria and proteinuria.Diabetes is a risk factor for coronary artery disease and congestive heart failure.The present study is aimed to assess cardiac function in diabetes and prevalence of diabetic complications and the relation to glycaemic control in these patients.Aims and Objectives-1.To assess cardiac function in 30 cases of diabetes mellitus.2. To assess the prevalence of complications.3. To assess the relation of glycaemic control to complications. 4. Prevalence of other risk factors. MATERIALS AND METHODSThirty consecutive patients with diabetes of 5 to 10 years duration, attending the diabetic clinic of Govt.Medical College, Kozhikode, Kerala were randomly selected.Detailed history regarding onset and duration of diabetes, symptoms of target organ involvement was taken.Detailed clinical examination and necessary investigations were done. RESULTS1. Retinopathy was present in 43.33%; 2. Proteinuria was present in 40%; 3. Neuropathy was present in 56-66%; 4. Commonest lipid abnormality was increased HDL followed by low LDL; 5. LV mass was increased; 6. Exercise stress test was positive in 30%; 6. Diastolic dysfunction was present in 26.66%; 7. Increase in mean IVS thickness was noted. CONCLUSION1. Diastolic dysfunction is common in diabetes (26.66% in this study); 2. Subclinical ischaemic heart disease contributes more to cardiac dysfunction in diabetes than diabetic cardiomyopathy (75% in this study); 3. Left ventricular mass is increased in diabetic patients; 4. Silent ischaemia is common in diabetes (30% in this study).
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Mridulkumar Kannath (2018) conducted a cross-sectional in Diabetes Mellitus (n=30). Diabetes Mellitus was evaluated on Prevalence of diastolic dysfunction and silent ischemia. In patients with diabetes mellitus for 5 to 10 years, diastolic dysfunction was present in 26.7% and silent ischemia in 30%, suggesting subclinical ischemic heart disease is a major contributor to cardiac dysfunction.
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