Key result
Obesity is linked to a ~30% increased risk of developing HF.
Why the study?
Obesity is associated with increased cardiovascular risk and heart failure, but it remains difficult to distinguish symptoms caused by obesity alone versus obesity cardiomyopathy.
Obesity is associated with significant cardiac remodeling, including left ventricular hypertrophy and dilatation, leading to an increased risk of heart failure.
Obesity and heart failure are a global epidemic associated with increased cardiovascular risk and significant health-care costs.1 2 Epidemiological evidence suggests that obese patients are 30 % more likely to develop heart failure3 and each incremental body mass index (BMI) rise of 1 kg/m2 can increase the risk of heart failure by 5 % for men and by 7 % for women.4 Moreover, heart weight and body weight have a linear relationship,5 and long-term obesity is associated with left ventricular hypertrophy and dilata-tion, which may result in cardiac failure. It remains difficult to distinguish whether symptoms of poor exercise tolerance, dyspnoea and peripheral oedema are secondary to obesity alone or ‘obesity cardiomyopathy ’. On echocardiography left ventricular dilatation is present in 8e40 % of obese individuals, and increased left ventricular wall mass exists in up to 87 % of obese patients.6
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Ashrafian et al. (2010) conducted a review in Obesity and heart failure. Obesity was evaluated. Obesity increases the risk of developing heart failure by 30%, with each 1 kg/m2 rise in BMI increasing the risk by 5% for men and 7% for women.
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