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November 17, 2003Human MutationOpen Access

Detailed analysis of five mutations in dihydropyrimidine dehydrogenase detected in cancer patients with 5-fluorouracil-related side effects

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Authors

EGEva GroßLMU KlinikumTUTobias UllrichUniversity of StuttgartKSKatharina SeckUniversität Hamburg

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Groß et al. (2003) studied this question.

synapsesocial.com/papers/6aab61ddba1d56de2cf9918fhttps://doi.org/10.1002/humu.9201
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  1. 1Identification of specific BRCA1 and BRCA2 variants by DHPLC2000 · 75 citations
  2. 2Crystal Structure of the Productive Ternary Complex of Dihydropyrimidine Dehydrogenase with NADPH and 5-Iodouracil2002 · 64 citations
  3. 3A comparative analysis of translated dihydropyrimidine dehydrogenase cDNA; conservation of functional domains and relevance to genetic polymorphisms2002 · 50 citations