Key result
Balloon-augmented leaflet laceration achieves 100% success in patients at risk for inadequate splay during transcatheter valve replacement.
Why the study?
BASILICA and LAMPOON may fail to prevent obstruction due to inadequate leaflet splay in patients with challenging anatomy during transcatheter valve replacement procedures.
Does balloon-augmented leaflet laceration improve leaflet splay and prevent obstruction in patients undergoing TAVR or TMVR with challenging anatomy?
Comparison
Balloon-augmented leaflet laceration vs traditional BASILICA or LAMPOON
Design
Observational case series at 3 centers with in vitro benchtop validation
Follow-up
30 days
Authors
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May facilitate leaflet modification during transcatheter valve replacement in high-risk anatomy; leaves open the need for larger prospective validation.
Observational (n=20)
Yes
Does balloon-augmented leaflet laceration improve leaflet splay and prevent obstruction in patients undergoing TAVR or TMVR with challenging anatomy?
Balloon-augmented leaflet laceration is a feasible technique that enhances leaflet splay and may enable TAVR and TMVR in patients with challenging anatomy who are ineligible for traditional BASILICA or LAMPOON.
Perdoncin et al. (2021) conducted an observational in Risk of coronary and left ventricular outflow obstruction during TAVR and TMVR (n=20). Balloon-augmented (BA) leaflet laceration (BA-BASILICA and BA-LAMPOON) was evaluated on Successful target leaflet laceration. Balloon-augmented leaflet laceration achieved 100% successful target leaflet laceration in 20 patients at risk for inadequate splay during transcatheter valve replacement.
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