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April 3, 2019Annals of SurgeryOpen Access

Patient Behaviors and Characteristics Related to Weight Regain After Roux-en-Y Gastric Bypass

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Key result

Postsurgery binge eating and sedentary time linked to ~8% greater weight regain after gastric bypass.

  • MD 8.0%
  • 95% CI 5.1-11.0
  • n=1,278

Why the study?

There is considerable variation in the magnitude of weight regain after Roux-en-Y gastric bypass surgery, highlighting the importance of patient-level factors.

Do specific patient behaviors affect weight regain in adults after Roux-en-Y gastric bypass surgery?

Population

1278 adults who underwent RYGB with adequate follow-up from 6 US cities

Comparison

Specific postsurgery behaviors vs reference behaviors

Design

Prospective cohort study

Follow-up

Median 6.6 years

Authors

WKWendy C. KingSBSteven H. BelleAHAmanda S. Hinerman

Discussion

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Overview

May warrant postoperative behavioral screening after RYGB; hypothesis-generating and requires prospective trials before changing practice.

Study Design

Type

Cohort (n=1,278)

Multicenter

Yes

Structured PICO

Do specific patient behaviors affect weight regain in adults after Roux-en-Y gastric bypass surgery?

P
Population
1,278 adults (80% female, median age 46 years) who underwent Roux-en-Y gastric bypass surgery, followed for a median of 6.6 years.
E
Exposure
Specific postsurgery behaviors (sedentary time, eating fast food, eating when feeling full, eating continuously, binge eating, weighing oneself)
C
Comparator
Reference behaviors (e.g., lowest quartile of sedentary time, absence of binge eating)
O
Outcome
Weight regain (percentage of maximum weight lost calculated each year after weight nadir)surrogate

Main Result

Mean Difference: 8 (95% CI 5.1–11)

Specific postsurgery behaviors, such as binge eating and increased sedentary time, are independently associated with greater weight regain after Roux-en-Y gastric bypass.

Cite This Study

King et al. (2019) conducted a cohort in Weight regain after Roux-en-Y gastric bypass (n=1,278). Postsurgery eating behaviors and sedentary time vs. Reference groups (e.g., lowest quartile, absence of behavior) was evaluated on Weight regain (percentage of maximum weight lost) (MD 8.0%, 95% CI 5.1-11.0). Postsurgery behaviors including binge eating (mean difference 8.0%; 95% CI 5.1-11.0) and sedentary time were independently associated with weight regain after Roux-en-Y gastric bypass.

synapsesocial.com/papers/6aab73bc39deae26ca3e05e7https://doi.org/10.1097/sla.0000000000003281
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Review of the key results from the Swedish Obese Subjects (<scp>SOS</scp>) trial – a prospective controlled intervention study of bariatric surgery2013 · 1,839 citations
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  3. 3A systematic review and meta‐analysis on the longitudinal relationship between eating pathology and depression2016 · 205 citations
  4. 4Comparison of the Performance of Common Measures of Weight Regain After Bariatric Surgery for Association With Clinical Outcomes2018 · 409 citations
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