Key result
Adult head and neck soft tissue sarcomas show ~49% five-year overall survival and frequent recurrence.
Why the study?
Adult head and neck soft tissue sarcomas have a high mortality rate with high risk of local recurrence and metastatic disease, and optimal management strategies are unclear due to disease rarity.
Cohort (n=36)
No
Adult head and neck soft tissue sarcomas are associated with high mortality and recurrence rates, suggesting a need for centralized care to improve outcomes.
Poor survival and high recurrence in head and neck sarcomas; hypothesis-generating and requires validation in prospective cohorts.
We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median size of 5.5 cm. Eleven different histological subtypes were identified. Wide excision was possible only in 21% of the cases. 42% of the patients developed local recurrence and 42% developed metastatic disease usually in the lungs. Overall survival was 49% at 5 years. Tumour size was the most important prognostic factor. Adult head and neck soft tissue sarcomas have a high mortality rate with a high risk of local recurrence and metastatic disease. The rarity of the disease would suggest that centralisation of care could lead to increased expertise and better outcomes.
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Singh et al. (2008) conducted a cohort in Adult head and neck soft tissue sarcomas (n=36). Management of head and neck soft tissue sarcomas was evaluated on Overall survival at 5 years. Adult head and neck soft tissue sarcomas were associated with a 5-year overall survival of 49%, with 42% of patients developing local recurrence and 42% developing metastatic disease.
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