Key result
Aortic valve preservation reduces surgical mortality versus root replacement in acute type A dissection.
Why the study?
There is no consensus regarding the optimum surgical approach for acute type A dissection repair, with varying strategies and associated risks of reoperation.
Discusses surgical strategies for acute type A dissection, highlighting a preference for valve preservation except in connective tissue disorders, and notes risks of GRF glue and causes for reoperation.
Answers are grounded in this paper and cite their sources.
May inform surgical decisions in acute type A dissection; leaves open need for prospective validation before changing practice.
Acute type A dissection is the most taxing of cardiovascular emergencies.The extent of dissection and fragility of the aortic wall may pose difficulties during and after primary repair.Even those with an interest in the aorta are unlikely to treat more than 10 cases per year and there is no consensus regarding the optimum surgical approach.Treatment options range from localized repair of the ascending aorta with a crossclamp in place (whether or not the tear is found) to complete root and arch replacement.The introduction of biological glues in Europe has resulted in a preference for aortic valve preservation, rather than the more radical alternative of aortic root replacement.'Recently, excessive use of Gelatin Resorcine Formol (GRF) glue has been suspected to cause tissue necrosis.Nevertheless, hospital survival is the prime objective in this high risk condition and less radical procedures are associated with lower surgical mortality.*Our approach is therefore to perform aortic root replacement only in patients with the Marfan and Elhers-Danlos syndromes.We attempt to repair the root and conserve the valve in all other cases.A number of different pathological processes may lead to reoperation.Ineffective resuspension of the native aortic valve results in persistent aortic regurgitation and the need for valve replacement.
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Westaby et al. (2008) conducted a review in Acute type A dissection. Aortic valve preservation vs. Aortic root replacement was evaluated. Aortic valve preservation is preferred over aortic root replacement in acute type A dissection to reduce surgical mortality, reserving root replacement for Marfan and Ehlers-Danlos syndromes.
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