Key result
PTFE bypasses with distal vein cuffs linked to ~83% higher 2-year patency vs historical uncuffed grafts.
Why the study?
PTFE prosthetic bypasses in the lower extremity have poor patency rates, particularly in limb salvage cases without suitable autologous saphenous vein.
Does the adjunctive use of distal interposition vein cuffs improve graft patency and limb salvage in patients undergoing PTFE infrainguinal bypass for critical limb ischemia?
Comparison
PTFE bypasses with distal interposition vein cuffs vs previous PTFE bypasses without vein cuffs
Design
Prospective cohort study
Follow-up
Mean 10 months (range 2-30 months)
Authors
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Distal vein cuffs were associated with higher PTFE bypass patency; hypothesis-generating and requires randomized confirmation before practice change.
Cohort (n=42)
Does the adjunctive use of distal interposition vein cuffs improve graft patency and limb salvage in patients undergoing PTFE infrainguinal bypass for critical limb ischemia?
Absolute Event Rate: 64% vs 35%
The addition of distal interposition vein cuffs to PTFE infrainguinal bypass grafts improves 2-year patency and limb salvage rates in patients lacking a suitable autologous vein.
Peter J. Pappas (1997) conducted a cohort in Critical limb ischemia (n=42). PTFE bypasses supplemented by distal interposition vein cuffs vs. Previous PTFE bypasses without vein cuffs was evaluated on Cumulative 2-year life-table patency for all grafts. PTFE bypasses supplemented by distal interposition vein cuffs achieved a 2-year patency of 64% versus 35% for historical PTFE bypasses without vein cuffs.
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