Key result
Higher BMI predicts incident asthma in women better than metabolic syndrome, linked to ~19% greater risk.
Why the study?
It is hypothesized that the metabolic syndrome explains the association between BMI and asthma in adults, but the relative strengths of these associations were unclear.
Is body mass index or metabolic syndrome a stronger predictor of incident asthma in adults?
Cohort (n=4,619)
Is body mass index or metabolic syndrome a stronger predictor of incident asthma in adults?
Hazard Ratio: 1.19
p-value: p=<0.001
BMI is a stronger predictor of incident asthma among women than the metabolic syndrome, suggesting other obesity-associated factors drive the BMI-asthma association.
BMI may better stratify asthma risk in women than metabolic syndrome; leaves open whether non-metabolic obesity factors drive the association.
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Assad et al. (2013) conducted a cohort in Incident asthma (n=4,619). Body mass index (BMI) vs. Metabolic syndrome was evaluated on Incident asthma (new self-reported provider asthma diagnosis plus asthma symptoms and/or use of asthma medications) (HR 1.19, p=<0.001). Body mass index was a stronger predictor of incident asthma in women than metabolic syndrome (HR 1.19 per 5 units; P<0.001), remaining significant after adjustment.
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