Key result
Amateur marathon running correlates with higher global wasted work and lower efficiency versus healthy controls.
Why the study?
The hyperphysiological stress response induced by marathon exercise in non-professionally trained athletes may lead to heart fatigue and organic changes, necessitating early detection of abnormal cardiac function.
Does amateur marathon running alter left ventricular systolic function as assessed by myocardial work parameters compared to healthy controls?
Population
35 amateur marathon runners and 33 age-matched healthy controls from Hangzhou
Comparison
Amateur marathon runners vs age-matched healthy controls
Design
Cross-sectional study
Authors
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May indicate subclinical LV inefficiency in amateur runners; hypothesis-generating and requires prospective validation before clinical relevance.
Cross-Sectional (n=68)
Does amateur marathon running alter left ventricular systolic function as assessed by myocardial work parameters compared to healthy controls?
Effect estimate: AUC 0.681 (95% CI 0.551-0.812)
p-value: p=<0.05
Non-invasive myocardial work assessment reveals subclinical changes in left ventricular systolic function, including increased wasted work and decreased efficiency, in amateur marathon runners.
Guo et al. (2024) conducted a cross-sectional in Left ventricular systolic function (n=68). Amateur marathon running vs. Age-matched healthy controls was evaluated on Global work efficiency (GWE) for predicting LV systolic function (AUC 0.681, 95% CI 0.551-0.812, p=<0.05). Amateur marathon running was associated with higher global wasted work and lower global work efficiency compared to healthy controls (P<0.05), with GWE yielding an AUC of 0.681.
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