Key result
Adding the D'Hoore-adapted Charlson comorbidity index improves long-term survival prediction in suspected AMI.
Why the study?
It was uncertain whether the Charlson comorbidity index computed from ICD-9-CM discharge diagnosis codes adds information beyond adjustment for disease severity, history, age, and sex in predicting long-term survival after suspected AMI.
Does the Charlson comorbidity index computed from ICD-9-CM discharge diagnosis codes improve the prediction of long-term survival in patients admitted for suspected acute myocardial infarction?
Cohort
Does the Charlson comorbidity index computed from ICD-9-CM discharge diagnosis codes improve the prediction of long-term survival in patients admitted for suspected acute myocardial infarction?
p-value: p=<0.001
The D'Hoore-adapted Charlson comorbidity index computed from ICD-9-CM codes is a useful risk adjustment tool for predicting long-term survival in patients with suspected AMI and angina.
Supports adapted Charlson index for AMI risk adjustment; extends validation in observational data but leaves clinical adoption open.
This study aims to determine whether the Charlson comorbidity index computed from ICD-9-CM discharge diagnosis codes adds additional information to a model containing adjustment for more informed patient details (e.g., disease severity and history), besides solely age and sex, when predicting long-term survival. We conducted a retrospective cohort study of patients admitted to hospital for suspected acute myocardial infarction. Index scores were calculated by applying the D'Hoore et al. algorithm (1993). The index significantly improved the model fit (likelihood ratio test: p < 0.001). The D'Hoore-adapted Charlson index is a useful comorbidity risk adjustment tool when applied to AMI and angina patients.
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Lim et al. (2000) conducted a cohort in Suspected acute myocardial infarction. Charlson comorbidity index computed from ICD-9-CM discharge diagnosis codes vs. Model containing adjustment for patient details without the index was evaluated on Model fit for predicting long-term survival (p=<0.001). The D'Hoore-adapted Charlson comorbidity index significantly improved model fit for predicting long-term survival in patients with suspected acute myocardial infarction (p < 0.001).
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