Key result
Physical activity improves cardiovascular function via molecular adaptations, rivaling drug treatments in some cardiac conditions.
Why the study?
The molecular mechanisms by which physical exertion affects cardiovascular function and disease outcomes require comprehensive analysis to inform rehabilitation.
Does physical exercise improve cardiovascular function and outcomes in patients with cardiac diseases?
Does physical exercise improve cardiovascular function and outcomes in patients with cardiac diseases?
Regular physical exercise induces molecular and cellular adaptations that improve cardiovascular function, offering therapeutic benefits comparable to pharmacotherapy in cardiac patients.
Exercise may complement pharmacotherapy in cardiac disease; leaves open equivalence in randomized trials.
The review analyzes the data of scientific publications on the effects of molecular mechanisms initiated by physical exertion on thefunction of the cardiovascular system and the course of cardiac diseases. As practice and a number of evidence-based studies haveshown, the beneficial effects of physical activity on the outcomes of diseases in a number of cardiac nosologies are comparable todrug treatment. Numerous mechanisms mediate the benefits of regular exercise for optimal cardiovascular function. Exercises causewidespread changes in numerous cells, tissues, and organs in response to increased metabolic demand, including adaptation of thecardiovascular system. Physical exercises, which include various types of aerobic exercises of varying intensity and duration, is animportant component of the therapeutic treatment of patients with cardiovascular diseases. Knowledge of the molecular basis ofthe physical activity impact on the cardiovascular system makes it possible to use biochemical markers to assess the effectiveness ofrehabilitation programs.
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Vladimirsky et al. (2021) conducted a review in Cardiovascular diseases. Physical activity was evaluated. Physical activity induces widespread molecular adaptations that benefit cardiovascular function, with effects comparable to drug treatment in some cardiac conditions.
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