Why the study?
Obesity hypoventilation syndrome is a severe consequence of obesity with increasing prevalence and challenges in diagnosis and management.
Population
Individuals with obesity hypoventilation syndrome defined by awake hypoventilation and BMI ≥30 kg/m2
Comparison
Positive airway pressure therapy and weight-loss interventions including bariatric surgery
Design
Concise clinical review
Key result
Positive airway pressure therapy is the mainstay of treatment for obesity hypoventilation syndrome, improving sleep disordered breathing and daytime hypercapnia, while weight loss can resolve the disease.
Authors
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Supports PAP and weight loss for OHS hypercapnia; leaves open optimal strategies pending prospective trials.
Untreated obesity hypoventilation syndrome leads to increased morbidity and mortality, highlighting the need for early recognition and treatment with positive airway pressure therapy and weight loss.
Greer et al. (2020) conducted a review in Obesity Hypoventilation Syndrome. Positive airway pressure therapy is the mainstay of treatment for obesity hypoventilation syndrome, improving sleep disordered breathing and daytime hypercapnia, while weight loss can resolve the disease.
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