Key result
Left ventricular outflow tract obstruction in hypertrophic cardiomyopathy is associated with a two-fold relative risk of sudden death (RR 2.0), but its low positive predictive value (<10%) limits its utility for primary prevention ICDs.
Why the study?
Does prophylactic ICD implantation prevent sudden cardiac death in HCM patients with LV outflow tract obstruction?
Population
Patients with hypertrophic cardiomyopathy (HCM)
Design
Editorial
Authors
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Resting LV outflow tract obstruction in HCM has a low positive predictive value for sudden cardiac death and should not be used as a sole indication for primary prevention ICD implantation.
Does prophylactic ICD implantation prevent sudden cardiac death in HCM patients with LV outflow tract obstruction?
Relative Risk: 2
Resting LV outflow tract obstruction in HCM has a low positive predictive value for sudden cardiac death and should not be used as a sole indication for primary prevention ICD implantation.
Maron et al. (2006) conducted an editorial in Hypertrophic cardiomyopathy. Left ventricular outflow tract obstruction vs. Non-obstructive patients was evaluated on Sudden cardiac death (RR 2.0). Left ventricular outflow tract obstruction in hypertrophic cardiomyopathy is associated with a two-fold relative risk of sudden death (RR 2.0), but its low positive predictive value (<10%) limits its utility for primary prevention ICDs.
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