Key result
Inherited and acquired thrombophilia in pregnancy are linked to increased vascular placental pathologies and poor outcomes.
Why the study?
Inherited and acquired thrombophilia are major causes of thrombosis in pregnant women and are associated with increased vascular pathologies leading to poor gestational outcomes.
This review discusses the association between thrombophilia and vascular placental pathology, as well as therapeutic modalities to improve gestational outcomes.
Thrombophilia may link to placental vascular pathology and adverse outcomes; leaves open optimal anticoagulation strategies pending controlled trials.
Inherited and acquired thrombophilia are the main cause of thrombosis in pregnant women. A growing number of reports over the last few years have suggested that these disorders are also associated with an increased incidence of vascular pathologies resulting in poor gestational outcome. This article discusses recent data concerning thrombophilia and vascular placental pathology, and discusses available therapeutic modalities to prevent placental vascular thrombosis and maximize successful gestational outcome.
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Benjamin Brenner (2005) conducted a review in Thrombophilia in pregnancy. Thrombophilia was evaluated. Inherited and acquired thrombophilia in pregnant women are associated with an increased incidence of vascular placental pathologies and poor gestational outcomes.
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